Basal-like breast carcinomas (BLCs) present with extratumoral lymphovascular invasion, are highly metastatic, presumably through a hematogenous route, have augmented expression of CD44 oncoprotein and relatively low levels of retinoblastoma (Rb) tumor suppressor.However, the causal relation among these features is not clear.Here, we show that Rb ac
Antiproliferative Effect of Acridine Chalcone Is Mediated by Induction of Oxidative Stress
Chalcones are naturally occurring phytochemicals with diverse biological activities including antioxidant, antiproliferative, and anticancer effects.Some studies indicate that the antiproliferative effect of chalcones may be associated with their pro-oxidant effect.In Apparel the present study, we evaluated contribution of oxidative stress in the a
Isofront in the Eastern Siberian Region (1930s)
The history of the formation of the organization of the Union of Soviet Artists in the remote regions of the country has not been fully studied, Bath Bombs but it is of interest for understanding the features of the development of domestic fine art.The article discusses the process of formation of branches of the East Siberian Regional Union of Sov
Plant-Derived Anti-Inflammatory Compounds: Hopes and Disappointments regarding the Translation of Preclinical Knowledge into Clinical Progress
Many diseases have been described to be associated with inflammatory processes.The currently available anti-inflammatory drug therapy is often not successful or causes intolerable side effects.Thus, new anti-inflammatory substances are still urgently needed.Plants were the first source of remedies in the Bump Mask history of mankind.Since their che